The Kanzius RF Field Generator
Cost to Develop: $1 million+Time: 5 yearsPrototype | | | | | Product

When a man with no medical degree and a diagnosis of fatal leukemia builds a cancer-curing machine in his garage, you might think it merely the desperate attempt of a dying man to escape his fate. And youd be right. The weird thing is, it just might work.

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K3 Promoter
Cost to Develop: $100,000
Time: 8 years
Prototype | | | | | Product
Gordon Link, a diabetic and foot amputee, is not looking to climb Mount Everest, run a marathon, or snowboard off a cliff. I just want to walk without stumbling like Im a drunk, he says. It may not sound like a tall order, but until he was fitted with a prototype prosthetic foot that simulates the bodys natural movements, walking on uneven ground was like navigating an obstacle course. Hitting a low spot of even one inch with my old foot was like a non-amputee stepping into a four-inch hole, he adds. Not good.

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Uno
Cost to Develop: $45,000
Time: 2 years
Prototype | | | | | Product
Just before his plane dipped into the clouds above Beijing International Airport two years ago, Ben Gulak caught the last clear view of the sun that he would see for two weeks. On the ground, the 17-year-old, who was on a family trip to China, quickly spotted a source for much of the thick haze hanging over the city: smog-spewing motorbikes. Thousands of them, everywhere. “Right then,” he says, “I decided that I wanted to create an alternative mode of transportation, something clean and compact.”

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Viper
Cost to Develop: $250,000Time: 2 yearsPrototype | | | | | Product
If were ever going to see a true era of commercial space travel—a day when Virgin Galactic is just another spaceline—Tim Bendel believes we need a better rocket engine. Specifically, something that is to the space industry what the internal combustion engine was to the nascent car industry a century ago: a standard, off-the-shelf option that can power any manner of vehicle, from tourist ship to lunar lander. And it has to be affordable to companies not owned by billionaire Richard Branson.

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Sky Serpent
Cost to Develop: $250,000
Time: 9 years
Prototype | | | | | Product
Today’s largest wind farms are the size of small towns, made up of turbines 30 stories tall with blades the size of 747 wings. Those behemoths produce a great deal of power, but manufacturing, transporting, and installing them is both expensive and difficult, and back orders are common as the industry grows by more than 40 percent a year. The solution, says inventor Doug Selsam, is to think smaller: Capture more power with less material by putting 2, 10, someday dozens of smaller rotors on the same shaft linked to the same generator.

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InSeT System
Cost to Develop: $475,000
Time: 2 years
Prototype | | | | | Product
In January 2006, an explosion rocked West Virginias Sago coal mine, trapping 13 miners. Rescuers searched an area 500 feet wide by two miles long and didnt reach the miners until 41 hours after the blast, eventually pulling out 12 bodies and one survivor. Jim Ponceroff, who led a rescue team, says that the biggest challenge in recovering miners is locating them quickly so that engineers can drill a borehole for fresh air and, ultimately, rescue. Sago, like most of the countrys nearly 900 active mines, relied on radios that transmit signals over a thin wire thats easily damaged in a cave-in.

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Bel-Air
Cost to Develop: $236,000
Time: 1 year
Prototype | | | | | Product
Your home could be emitting toxic gases. Just ask the victims of Hurricane Katrina, whose emergency trailers, made with glue-laden particleboard, let off so much formaldehyde that the Centers for Disease Control and Prevention warned that residents should spend time outdoors and make relocating to permanent housing a priority. Even in more expensive new homes, the concentration of emissions from things like furniture, carpet and paint can be two to five times as high as it is outdoors. But most air filters only catch particulates such as dust and pollen rather than organic compounds like formaldehyde and benzene, and the filters that do trap those gases need frequent replacement. So Mathieu LeHanneur and David Edwards built an ultra-efficient filtration system that eliminates toxins using natures own hazmat squad: plants.

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Hillman Composite Beams
$500,000
Time: 12 years
Prototype | | | | | Product
Last November, John Hillman stood beneath a bridge built with prototype plastic-and-concrete beams of his own design. Then he signaled for his team to release a nine-million-pound coal train. “You can do all the calculations you want; you can do tons of lab testing. But at the end of the day, you run a heavy-axle coal train over the bridge, and that pretty much tells you whether or not it’s gonna hold,” Hillman says. It didn’t budge.

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Paragon Diving System
Cost to Develop: $1.2 million
Time: 7 years
Prototype | | | | | Product
Diesel oil and raw sewage slowly trickled into Taber MacCallums eyes as he swam toward the sunken research ship hed been called to help salvage. It was 1989, and Hurricane Hugo had devastated Puerto Rico three days before, dumping fuel and municipal waste into San Juan Harbor. As the young diver and analytical chemist worked to raise the ship, the seals on his diving equipment disintegrated in the muck that crept into his helmet. Every time MacCallum exhaled into the putrid water, his helmet let a few drops back in.

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The Cyclone
Cost to Develop: $2 million
Time: 8 yearsPrototype | | | | | Product
As long as the internal combustion engine has been around, garage tinkerers have been trying—in vain—to best it. But Florida boat engineer Harry Schoell, a lifelong inventor with a portfolio of patents, thinks hes got the answer, in the form of a reinvented steam engine.

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Tired of car chases, robberies, and general action-packed anarchy? Set aside Grand Theft Auto IV for a minute and enter a new kind of gaming adventure: the exciting world of protein folding! Researchers at Howard Hughes Medical Institute and the University of Washington have developed Foldit, a free, online game in which players compete to design proteins.

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We have all at one point or another learned some variation of a mathematical formula involving trains and their timetables. For example: if a train leaves Boston for New York at 7am and travels at 60mph, will it beat a train leaving Providence at 6am traveling 45mph? The idea behind this kind of "story" problem is to engage a student with a real-world example to which they can relate. The thinking follows that that engagement will solidify the mathematical concept. It's one of those conceits that has hung around for seemingly as long as math has been taught. And it may very well be completely wrong.

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In the world of cinematic science fiction one of the most appealing themes involves a universe brimming over with intelligent life. In this imagined future (or past) humans interact with alien friend and foe because they've at last hammered down the ability to travel to distant stars and galaxies, and, yes, "to boldly go where no man has gone before. Having grown up on the original Star Trek series, observed the effect of the Star Wars movies on the zeitgeist of movie-going generations and enjoyed sci-fi soap operas like Battlestar Galactica, I have to admit I wish we could make it happen; no matter the odds.

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Let's get to the limitations right away: Mac and even Firefox users will have to sit this one out, since it only runs on a PC, in Internet Explorer. And XP is probably your best bet, too, since Vista users have apparently reported some glitches when using the beta version of this very cool new interactive tool.

All that aside, though, the Visible Body, a new, and free, interactive experience from Argosy Publishing, is pretty mind-blowing. It's Gray's Anatomy in 3-D. (The book, people, not the show.)

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